49  细菌长度和宽度

细菌长度和宽度测量

1. 理论基础

细菌形态的变化可能受制于营养物质可及性、抗生素暴露、基因突变等因素(1)，因此可以为一个评价指标(1),(2)。

2. 流程和实例

说明：示例图片来自Omnipose (3)，且未按照等比例展示。流程部分内容参考自(4)。

给我买杯茶🍵

References

1.

N. Ojkic, D. Serbanescu, S. Banerjee, Surface-to-volume scaling and aspect ratio preservation in rod-shaped bacteria. eLife 8 (2019).

2.

A. N. Bible, B. B. Stephens, D. R. Ortega, Z. Xie, G. Alexandre, Function of a chemotaxis-like signal transduction pathway in modulating motility, cell clumping, and cell length in the alphaproteobacterium azospirillum brasilense. Journal of Bacteriology 190, 6365–6375 (2008).

3.

K. J. Cutler, C. Stringer, T. W. Lo, L. Rappez, N. Stroustrup, S. Brook Peterson, P. A. Wiggins, J. D. Mougous, Omnipose: A high-precision morphology-independent solution for bacterial cell segmentation. Nature Methods 19, 1438–1448 (2022).

4.

B. S. Monteiro, K. Wu, The lengths of bacilli after omnipose (2025). https://forum.image.sc/t/the-lengths-of-bacilli-after-omnipose/117452.